Generally any of the proposed research projects can be performed at different
levels of complexity, from a 3 month undergraduate research project to
pursuing a master by research or PhD degree. Have a look at the various
research areas shown on our related webpages so that you could identify
one (or several areas) that are of particular interest to you.
Staff members of our group are experienced in supervision of research projects.
We generally provide plenty of consultation time and academic support during
the project. However, we expect students to do .their homework. and also give
timely notice if any problems are encountered, so that we are able to resolve
these and make good progress for completion of the project. We also encourage
that students publish journal and conference papers as they do their research,
as this is beneficial on several levels. If you have any questions regarding
research topics we are happy to further discuss them with you.
Some Selected Research Projects
While the list of projects given below is not "inclusive" - it represents a variety
of different research topics which we are interested in:
- Cartilage mechanics and biosynthesis of cartilage: How does cartilage
perform its biological function? How can this tissue be regenerated after injury?
- Bone regulation . from health to disease: How do bone cells interact
with each other to rebuild new bone? Why does osteoporosis occur and how can
we effectively treat this disease?
- Cancer metastasis formation in bone: Why do cancer cells metastasis
to bone? How do cancer cell utilize bone cells in order to grow? Can we
interrupt this interaction in order to slow down tumor growth?
- Prostate cancer development:
- Wnt signaling in mammalian cells:
- Design of a glaucoma implant:
- Development of a computational tool to predict preterm birth: Can we
identify risk factors for women giving birth prematurely? What are determinants of
premature birth? Is it possible to use statistical methods to estimate this risk?
- Signal mechanotransduction in bone: How do bone cells sense their
mechanical environment? How is mechanical loading integrated in the bone
remodeling process? We aim to develop a coupled fluid-solid deformation
model which helps answering some of these questions.
- Optimization of 3D scaffolds used as bone replacement materials:
What are ideal pore structures of bone replacement materials so that
bone cells can grow? Can we design materials which have similar mechanical
properties as bone?