Calcium oscillations in smooth muscle
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    Calcium oscillations in smooth muscle

    Slow waves are rhythmic electrical depolarizations that initiate and control mechanical activity of many smooth muscles. The mechanism responsible for generating slow waves involves inositol 1,4,5-trisphosphate (IPB 3B )-induced CaP 2+P release (IICR) and calcium-induced calcium release (CICR) from IPB 3B -operated intracellular CaP 2+P stores. We have been developing a qualitative mathematical model to examine membrane potential feedback on synthesis of inositol 1,4,5-trisphosphate, and its role in generation and modulation of slow waves.




        Groovy biomedical image Scanning confocal microscope image of fluorescent dye indicating calcium in smooth muscle cells (van Helden and Imtiaz 2003)  

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Last updated: July 15 2015 09:16:55.